新颖实用的有机合成研究和合成方法的探索； 具有生物活性的天然小分子的合成及其类似物的设计、合成和生物活性研究； 精细化学品合成及工艺研究； 电子产品清洗剂研究。

1986-09至1990-07，北京化工大学，应用化学系，学士

2000-09至2005-06，BETVLCTOR伟德在线登录平台，BETVlCTOR登录网站，博士 

1990-07至2000-08，天津化工厂，工程师

2005-07至现在，       BETVLCTOR伟德在线登录平台，BETVlCTOR登录网站，副教授

2016-07至2017-07，美国加州大学圣巴巴拉分校，访问学者

主持完成国家自然科学基金面上项目2项，天津市面上项目2项，并参与多项国家基金项目的研究工作，完成多项精细化工应用项目。研究工作已经发表研究论文30余篇；申请发明专利16项，国际专利2项，其中授权专利12项。

1. Triangular rhodamine triads and their intrinsic photophysics revealed from gas-phase ion fluorescence experiments, Zhao, Y., Sørensen, E. R., Lindkvist, T. T., Kjær, C., Nielsen, M. B., Chen, L.*, Nielsen, S. B.* Chem. Eur. J. 2021, 27, 10875–10882.

2. Gas-phase Förster resonance energy transfer in mass-selected ions with methylene or peptide linkers between two dyes: a concerted dance of charges,  Kjær, C.; Zhao, Y.; Stockett, M. H.; Chen, L.*; Hansen, K.; Nielsen, S. B.. Phys. Chem. Chem. Phys, 2020, 22, 11095-11100.

3. Enantioselective and regioselective aza-Friedel–Crafts reaction of electron-rich phenols with isatin-derived ketimines. Cai, L.; Liu, X. S. Wang, J.; Chen, L.; Li, X.*; Cheng, J. P. Chem. Commun., 2020, 56, 10361—10364. 

4. Bi(OAc)3/Chiral Phosphoric Acid Catalyzed Enantioselective Allylation of Seven-Membered Cyclic Imines Dibenzo[b, f][1,4]oxazepines. Cai, L.; Pan, Y. L.; Chen, L.; Cheng, J. P.; Li, X.* Chem. Commun., 2020,  DOI: 10.1039/  d0cc05855f

5. Metal-Free Direct C-H Cyanoalkylation of Quinoxalin-2(1H)-Ones by Organic Photoredox Catalysis. Zhang, W.; Pan, Y. L.; Yang, C.; Chen, L.; Li, X.;* Cheng, J. P.; J. Org. Chem. 2019, 84, 7786-7795.

6. Silver-catalyzed stereoselective formation of glycosides using glycosyl ynenoates as donors, Dong, X.; Chen, L.*; Zheng, Z.; Ma, X.; Luo, Z.; Zhang, L., Chem. Commun., 2018, 54, 8626-8629.

7. Organocatalytic Asymmetric Sequential 1,6-Addition/Acetalization of 1-Oxotetra- lin-2-carbaldehyde to ortho-Hydroxyphenyl-Substituted para-Quinone Methides for Synthesis of Spiro-3,4-dihydrocoumarins. Zhang, Z. P.; Chen, L.;  Li, X.;*  Cheng, J. P.; J. Org. Chem. 2018, 83, 52714 – 2724.

8. Formation of β-Lactones by [2+2] Cycloaddition of Dichloroketene with Unreactive Carbonyl Compounds, Dong, X.; Zhang, C.; Xu, J.; Zhang, Y.; Zhao,Y.; Chen, L.*; Chem. Research Chin. Uni., 2018, 34, 736-743..

9. 叔胺硫脲催化的 ２,５⁃二羟基⁃１,４⁃二噻烷与氮叔丁氧羰基醛亚胺的不对称［３＋２］环化反应，董 旭，封博谞，陈 莉*，李 鑫，高等学校化学学报，2018, 39, 1707–1712.

10. Diastereoselective Synthesis of Cephalotaxus Esters via Asymmetric Mukaiyama Aldol Reaction, Ma, G. Z.; Li, P. F.; Liu, L.; Li, W. D.; Chen, L.* Org. Lett., 2017, 19, 2250–2253. (Highlights by Synfacts 2017, 13, 744)

培养硕士研究生11名。